Methods for Meta-Analysis in Medical Research医学研究中的META-分析方法 电子版 免费 pdf 下载 azw3 fb2 caj mobi

With meta-***ysis methods playing a crucial role in health research in recent years， this important and clearly-written book provides a much-needed survey of the field。

Meta-***ysis provides a framework for combining the results of several clinical trials and drawing inferences about the effectiveness of medical treatments。The move towards evidence-based health care and practice is underpinned by the use of meta-***ysis。 This book：

* Provides a thorough criticism and an up-to-date survey of meta-***ysis methods

* Emphasises the practical approach，and illustrates the methods by numerous examples

* Describes the use of Bayesian methods in meta-***ysis

* Includes discussion of appropriate software for each ***ysis

* Includes numerous references to more advanced treatment of specialist topics

* Refers to software code used in the examples available on the authors’ Web site

Practising statisticians， statistically-minded clinicians and health research professionals will benefit greatly from the clear presentation and numerous examples。 Medical researchers will gr*** the basic principles of meta-***ysis，and learn how to apply the various methods。

Preface xv

Acknowledgements xvii

Part A： Meta-Analysis Methodology： The Basics

1　Introduction - Meta-***ysis： Its Development and Uses

2　Defining Outcome Measures used for Combining via Meta-***ysis

3　Assessing Between Study Heterogeneity

4　Fixed Effects Methods for Combining Study Estimates

　5　Random Effects Models for Combining Study Estimates

　6　Exploring Between Study Heterogeneity

7　Publication Bias

　8　Study Quality

　9　Sensitivity Analysis

　10　Reporting the Results of a Meta-***ysis

Part B： Advanced and Specialized Meta-***ysis Topics

11　Bayesian Methods in Meta-***ysis

12　Meta-***ysis of Individual Patient Data

13　Missing Data

14　Meta-***ysis of Different Types of Data

15　Meta-***ysis of Multiple and Correlated Outcome Measures

16　Meta-***ysis of Epidemiological and Other Observational Studies

17　Generalized Synthesis of Evidence-Combining Different Sources of Evidence

18　Meta-***ysis of Survival Data

19　Cumulative Meta-***ysis

20　Miscellaneous and Developing Areas of Application in Meta-***ysis

AppendixⅠ：Software Used for the Examples in this Book

Subject index

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书籍介绍

With meta-***ysis methods playing a crucial role in health research in recent years, this important and clearly-written book provides a much-needed survey of the field. Meta-***ysis provides a framework for combining the results of several clinical trials and drawing inferences about the effectiveness of medical treatments. The move towards evidence-based health care and practice is underpinned by the use of meta-***ysis. This book: Provides a thorough criticism and an up-to-date survey of meta-***ysis methods Emphasises the practical approach, and illustrates the methods by numerous examples Describes the use of Bayesian methods in meta-***ysis Includes discussion of appropriate software for each ***ysis Includes numerous references to more advanced treatment of specialist topics Refers to software code used in the examples available on the authors' Web site Practising statisticians, statistically-minded clinicians and health research professionals will benefit greatly from the clear presentation and numerous examples. Medical researchers will gr*** the basic principles of meta-***ysis, and learn how to apply the various methods.